- The best dog dewormers should treat four of the most common intestinal parasites in dogs and should be easy to administer.
- Guaranteed to treat multiple species of hookworm, roundworm, tapeworm, and whipworm, Safe-Guard 4 Canine Dewormer is our top pick for the best dog dewormer overall.
- This article was medically reviewed by Karie Johnson, veterinarian and co-founder of VIP Vet Visit, a mobile vet service in the south suburbs of Chicago.
Intestinal parasites are extremely common in dogs of all ages, and most can’t be seen with the naked eye, which means you might not know if your dog is infected. Some worms can be transmitted to humans (children are especially vulnerable), so it’s important to keep your dog parasite-free.
When choosing the best dewormer for your dog, you need to know what type of worms your dog has. If you suspect that your dog might have worms, bring them to the veterinarian for a physical exam and fecal test. Treatment is generally easy with over-the-counter dewormers for dogs.
You can purchase a dewormer for specific types of worms, or you can choose a broad-spectrum product that kills many different types of worms. Dewormers come in several forms including tablets, granules, powders, and liquids, so talk to your veterinarian about the option that is best for your dog. Once you know what kind of dewormer you need, take a look at our top picks for the best non-prescription dewormer for dogs.
Here are the best dog dewormers you can buy:
- Best dog dewormer overall: Excel Safe-Guard 4 Canine Dewormer
- Best liquid dog dewormer: Nemex 2 Liquid Dewormer for Dogs
- Best dewormer for puppies: Bayer Quad Dewormer Chewable Tablets for Puppies and Small Dogs
- Best dewormer for small dogs: Sentry HC WormX Plus 7-Way Dewormer
- Best dewormer for large dogs: Durvet Triple Wormer for Medium and Large Dogs
Safe-Guard 4 Canine Dewormer (fenbendazole) is a broad-spectrum dewormer that kills four types of intestinal parasites commonly seen in dogs.
Pros: Kills four common types of worm, easy-to-mix granule formulation, safe and effective, kills two species of roundworm and hookworm
Cons: Large dogs may require more than one package, only kills one species of tapeworm and whipworm, three once-a-day doses required, not for puppies younger than 6 weeks of age
If you’re looking for a quick and effective solution to intestinal parasites, a broad-spectrum dewormer may be the way to go. These dewormers contain active ingredients that kill four types of common worms, including multiple species, and generally come in an easy-to-administer form. For efficacy, convenience, and affordability, Safe-Guard 4 Canine Dewormer is our top pick for the best dewormer for dogs overall.
Made with the active ingredient fenbendazole, Safe-Guard 4 Canine Dewormer kills two species each of roundworm and hookworm as well as the most common species of tapeworm and whipworm.
Generally recognized as a safe and effective dewormer for dogs, it comes in an easy-to-administer granule formulation that can be sprinkled on or mixed into your dog’s food and is safe for dogs and puppies 6 weeks or older. This dewormer is given once a day for three days. The American Animal Hospital Association recommends annual fecal tests to check for internal parasites at least once a year or as recommended by your veterinarian.
The best liquid dewormer for dogs
With pyrantel pamoate as the powerful active ingredient, Nemex-2 Liquid Dewormer is a safe and effective treatment for roundworms and hookworms in dogs and puppies as young as 2 weeks of age.
Pros: Highly palatable, liquid formulation is easy to administer, safe for puppies as young as 2 weeks, safe for pregnant females, good for dogs that don’t like tablets
Cons: Only treats roundworms and hookworms, large dogs may require a higher dosage
Many dogs dislike taking tablets and even powdered dewormers may be difficult to disguise in your dog’s food. If you’re looking for an alternative, a liquid dewormer might be a good option. Nemex 2 Liquid Dewormer for Dogs is our top pick because it is approved to treat roundworms and hookworms in dogs and comes in an easy-to-administer liquid.
Nemex 2 Liquid Dewormer for Dogs only treats roundworms and hookworms, so if your dog has tapeworms or whipworms, this medication will not be effective. The active ingredient pyrantel pamoate is highly effective and widely recognized as safe. Simply add the liquid to your dog’s food or feed it directly by mouth. One treatment should kill all worms. Follow up with a fecal test from your veterinarian to make sure the worms have been eliminated.
The best dewormer for puppies
Made with three powerful active ingredients, Bayer Quad Dewormer Chewable Tablets is a broad-spectrum dewormer safe for puppies and small dogs weighing at least 2 pounds and less than 25 pounds.
Pros: Three powerful active ingredients, broad-spectrum dewormer, kills four types of intestinal parasites, safe for puppies 2 pounds and over, palatable beef-flavored chewable tablet
Cons: Heavy infestations may require multiple treatments, some dogs dislike taking tablets
You may be surprised to learn that most puppies are born with worms. Fortunately, worms are generally easy to treat. Puppies should be treated with a dewormer at 2, 4, 6, 8 and 12 weeks of age, followed by additional treatments as needed. Our top pick for the best dewormer for puppies is Bayer Quad Dewormer Chewable Tablets.
Specifically designed for puppies and small dogs weighing between 2 and 25 pounds, Bayer Quad Dewormer Chewable Tablets features three active ingredients — praziquantel, pyrantel pamoate, and febantel — to kill four types of worms commonly seen in dogs: roundworms, hookworms, tapeworms, and whipworms. A single dose is enough to kill common worms and it comes in a highly palatable beef-flavored tablet. Follow up with a fecal test from your veterinarian to make sure the worms have been eliminated.
The best dewormer for small dogs
Fast-acting and cost-effective, this Sentry HC WormX Plus 7-Way Dewormer for Small Dogs kills seven species of roundworms, hookworms, and tapeworms.
Pros: Broad-spectrum dewormer, made for dogs 6 to 25 pounds, easy-to-administer tablet form, two powerful active ingredients, cost-effective
Cons: Doesn’t kill whipworms, not ideal for dogs over 25 pounds, not for use in puppies younger than 12 weeks, should not be used in pregnant or nursing females
Products designed for dogs of all sizes and dosed by weight can be tricky to divide for small-breed dogs, especially if they come in tablet form. For a safe and effective dewormer designed specifically for small dogs, we recommend Sentry HC WormX Plus 7-Way Dewormer for Small Dogs.
This Sentry Dewormer is formulated specifically for small dogs 12 weeks and older that weigh between 6 and 25 pounds. The two active ingredients, pyrantel pamoate and praziquantel, quickly and effectively kill two types of tapeworms, two types of roundworms, and three types of hookworms. It comes in an easy-to-administer tablet form that can be fed whole or crushed and mixed with your dog’s food. Only one dose is needed to eliminate worms. Follow up with a fecal test from your veterinarian to make sure the worms have been eliminated.
The best dewormer for large dogs
The Durvet Tripler Wormer for Medium and Large Dogs is an effective option for big dogs.
Pros: Broad-spectrum dewormer, two powerful active ingredients, made for dogs 25 to 200 pounds, palatable chewable tablet form, easy dosing instructions, works quickly
Cons: Doesn’t kill whipworms, not for dogs that weigh less than 25 pounds, not for puppies under 12 weeks of age
Large-breed dogs require different amounts of medicines, and that is definitely true for dewormers. If you purchase a regular dewormer, you may find yourself purchasing several boxes to get the right dosage for a large-breed dog. Depending what brand you choose, the costs to treat your dog could add up quickly — especially if the product requires multiple treatments.
For a fast and cost-effective solution designed specifically for medium and large breeds, we recommend Durvet Triple Wormer.
Durvet Triple Wormer features a broad-spectrum formula made with two powerful active ingredients: pyrantel pamoate and praziquantel. This product is proven to kill two species of tapeworms, two species of roundworms, and three species of hookworms.
It comes in a highly palatable chewable tablet. Simply feed it directly or mix it into your dog’s food. For the maximum efficacy, repeat the dosage after two weeks. As with the other dewormers on this list, follow up with a fecal test from your veterinarian to make sure the worms have been eliminated.
What you should know about intestinal parasites in dogs
Four different types of worms commonly infect dogs and puppies: roundworms, hookworms, tapeworms, and whipworms. Puppies are also commonly infected with a single-cell intestinal parasite known as coccidia. Adult dogs can become infected with coccidia as well, but many dogs develop an immunity to these parasites.
Dogs can become infected with intestinal parasites in different ways. Puppies often become infected with roundworms prior to birth or when nursing from their mother. Tapeworms can be transmitted if a dog swallows an infected flea (treating flea infestations goes hand in hand with treating tapeworm infections). Dogs can pick up hookworms and whipworms from their environment, often from the feces of infected dogs, or contaminated soil or water.
Some of the most common symptoms of worms in dogs included digestive upset (vomiting or diarrhea), gas, bloated belly (pot-bellied appearance), increased appetite, unexplained weight loss, weakness, and bloody stool or diarrhea. In puppies especially, intestinal parasite infections can cause anemia and poor growth.